Novel NIR DDNP-type solvatochromic and fluorogenic probes for amyloid β detection.
Selective near-infrared fluorescent probes for amyloid β aggregates are of considerable interest as molecular imaging tools for the diagnosis and study of Alzheimer's disease. Herein, we describe the rational design and synthesis of DDNP-type donor-π-acceptor fluorophores incorporating a fixed N,N-dimethylamino donor g...