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Author

Uma M. Basole

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Review Open access Aug 2026

The ERK MAPK pathway in mesenchymal glioblastoma: tumorigenesis, microenvironmental reprogramming, and the therapeutic promise of RAS(ON) multi-selective inhibition

The potential effect of daraxonrasib as an emerging targeted therapeutic candidate in MES-GBM is discussed, highlighting the need of further research and clinical evaluation to better determine its therapeutic efficacy dedicated GBM preclinical models.

Uma M. Basole, Mary M. Fitzpatric, Joseph I. Donohoe et al. · 0 citations

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