Author

Ufuk Ülker

3 papers indexed here

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Open access Oct 2026

Dose-Related Effects of Cannabidiol on Inflammatory and Redox Responses, Bacterial Dissemination, and Multiorgan Injury in CLP-Induced Septic Rats

Background: Sepsis couples dysregulated inflammation, oxidative imbalance, microbial dissemination, and multiorgan injury. Cannabidiol (CBD) has anti-inflammatory and redox-modulating properties, but its dose-related effects in polymicrobial sepsis, particularly alongside culture-recoverable bacterial burden, remain in...

Ufuk Ülker, B. Bayraktar, T. Karan et al. · Pharmaceuticals · 0 citations

Open access Oct 2026

Annona muricata Leaf Extract Rebalances Systemic Redox Status and Modulates Neuroimmune, Microbial, and Functional Responses in CLP-Induced Septic Rats

Oxidative stress, immune dysregulation, and disturbed metabolic adaptation contribute to early sepsis pathophysiology. This exploratory study evaluated a commercial Annona muricata leaf extract in 40 male rats assigned to five groups (n = 8/group): healthy Control, laparotomy-only Sham, untreated cecal ligation and pun...

Ufuk Ülker, B. Bayraktar, M. Alçığır et al. · Antioxidants · 0 citations

Open access Sep 2026

Effects of Moringa oleifera Oil on Adipokine Responses, Inflammation, Oxidative Stress, Bacterial Burden, and Early Survival in CLP-Induced Septic Rats

Findings support the attenuation of sepsis-associated lipid peroxidation but do not establish a direct antioxidant mechanism.

Ufuk Ülker, B. Bayraktar, M. Alçığır et al. · Antioxidants · 0 citations