Highlights What are the main findings? Nine studies involving 2062 patients with schizophrenia and comorbid substance use disorder (SUD) were included, with follow-up periods ranging from 6 months to 3 years. Several studies reported favorable clinical outcomes with long-acting injectable (LAI) antipsychotics, but the...
Matteo Lupi, A. Carano, Eros Rossi et al.· Brain Science· 0 citations
Antidepressant prescribing in major depressive disorder is guided by evidence-based recommendations, but real-world decisions often rely on clinical judgment, previous experience, and case-based reasoning. This study examined whether psychiatrists' routine prescribing decisions could be used to identify practice-ground...
Francesco Calabrò, Claudio Caiazza, U. Albert et al.· European Neuropsychopharmaco...· 0 citations
These findings suggest that standard clinical variables may hold predictive value for early readmission in MDD, however, external validation, assessment of model calibration, and clinical utility are needed prior to clinical implementation.
F. Bartoli, Mario Luciano, C. Crocamo et al.· Journal of Affective Disorde...· 0 citations
BACKGROUND
Depression is increasingly conceptualized as a biologically heterogeneous condition, with immune-inflammatory and metabolic dysregulation implicated in specific symptom dimensions rather than overall depressive severity. However, it remains unclear whether different combinations of inflammatory and metabolic...
M. Di Nicola, M. Pepe, A. Aguglia et al.· Psychoneuroendocrinology· 0 citations
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