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U. Panda

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Open access Sep 2026

Add-on intravenous ketamine eliminates treatment lag period in severe non-treatment-resistant major depression: Rapid antidepressant and anti-suicidal effects – A randomized controlled trial

ABSTRACT Background: The 4–12 week lag period of conventional antidepressants creates critical vulnerability in severe depression, with peak suicide risk during the first month. While ketamine research has focused on treatment-resistant populations, its potential to eliminate this lag period in non-treatment-resistant...

Anand Prakash, Pranab Mahapatra, J. Pattnaik et al. · 0 citations

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