Open access
Aug 2026
Structural and Biophysical Characterization of C‐Glycosylic 1,2‐Thiodisaccharides Reveals Determinants of Selective Binding to Galectin‐7 and Galectin‐8N
This work establishes C‐glycosylic thiodisaccharides as a robust platform for selective galectin targeting and provides actionable design principles for next‐generation inhibitors.
Anastasia S. Tsagkarakou, A. Kantsadi, Vasiliki I. Theodoridou et al.
· ChemMedChem · 0 citations