Author

U. Grošelj

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Open access Sep 2026

LDL hypercholesterolemia in children: genetic influence and response to lifestyle advice - follow-up of the Fr1dolin-trial

Although familial hypercholesterolemia (FH) is common and associated with significant cardiovascular morbidity, screening programs are scarce. Furthermore, the effectiveness of nutritional advice for parents on children’s LDL cholesterol (LDL-C) levels is unclear, especially in FH versus non-FH hypercholesterolemia. In...

S. Arens, U. Šuštar, K. Lange et al. · Lipids in Health and Disease · 0 citations

Review Open access Sep 2026

CREB3L3 associated severe hypertriglyceridemia: targeted NGS identification of a novel truncating variant and systematic review

Cyclic AMP Responsive Element Binding Protein 3 Like 3 (CREB3L3 ) plays a crucial role in hepatic triglyceride (TAG) metabolism. Variants in CREB3L3 have been reported in individuals with hypertriglyceridemia (HTG). In this article we present a family from Punjab, Pakistan, with a rare heterozygous CREB3L3...

Q. Ain, Madeeha Khan, Natalia Azhar et al. · Orphanet Journal of Rare Dis... · 0 citations

Open access Sep 2026

Effect of rosuvastatin and ezetimibe therapy on LDL-cholesterol reduction and non-invasive arterial injury markers in children with heterozygous familial hypercholesterolemia: a prospective, open-label, randomized study

Background and aims Individuals with familial hypercholesterolemia (FH) require early lipid-lowering therapy (LLT). We compared rosuvastatin versus ezetimibe treatment and the role of major non-invasive arterial injury markers in children with heterozygous FH. Methods In this prospective, open-label, randomized study,...

A. Skarlovnik, Tevž Gorjanc, J. Šikonja et al. · Frontiers in Cardiovascular... · 0 citations