A comprehensive molecular profile of melanomaassociated genes is provided, identifying critical pathways that could serve as potential therapeutic targets and associations with specific metabolites and drug responses offer new avenues for personalized medicine approaches in melanoma treatment.
J. Brahmaiah, U. Adiga, Vijay Kumar et al.· Research journal of biotechn...· 0 citations
To characterise temporal trends in reported dengue cases and deaths in India from 2010 to 2023, and compare case fatality ratios from two independent official government data streams, it is necessary to assess state-level distribution and serotypic patterns; and to synthesise published seroprevalence estimates from dis...
U. Adiga, S. Vasishta· Journal of Vector Borne Dise...· 0 citations
Aim: Age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, with genetic factors strongly influencing onset and progression. This study aimed to analyse GWAS data to identify AMD-associated genetic variants and explore their biological and regulatory significance.
Methodology: Public...
Loya Geeta Anusha, N. Uday Kumar, E. V. Ravikanth et al.· Journal of environmental bio...· 0 citations
These findings underscore the multifactorial nature of ALS across genetic, molecular and metabolic dimensions, identifying potential molecular targets to guide future therapeutic development.
U. Adiga, P. Supriya, S. Adiga et al.· Journal of environmental bio...· 0 citations
Multiple genetic loci were identified, reaffirming the contribution of immune dysregulation and impaired skin barrier function in psoriasis and reaffirming the contribution of immune dysregulation and impaired skin barrier function in psoriasis.
B. S. Sindhu, G. P. Chandrasekhar Naidu, Kukkapalli Prathap Kumar et al.· Journal of environmental bio...· 0 citations
A comprehensive genetic and molecular landscape underlying childhood obesity is delineated, reflecting its multifactorial pathogenesis, with implications for improving future prevention and management strategies for childhood obesity.
T. Govardhan, J. Brahmaiah, P. Kumar et al.· Journal of environmental bio...· 0 citations
This comprehensive analysis indicates that dysregulation of lipid metabolism is a major pathway in MetS, with specific miRNAs functioning as critical regulatory molecules and potential therapeutic strategies targeting miRNA-mediated regulation of lipid metabolism are suggested.
C. Deepthi, E. V. Ravikanth, P. Reddemma et al.· Journal of environmental bio...· 0 citations
Novel insights are revealed into CHD genetics, confirming known loci such as 9p21.3 (CDKN2B-AS1), COL4A2 and PHACTR1, while uncovering their broader functional roles in vascular remodelling, inflammation, and lipid metabolism.
T. Amulya, S. Vadlamudi, K. Farzia et al.· Journal of environmental bio...· 0 citations
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