Trilok Chand Saini

Nano-catalytic carbon dot disrupts hypoxia-driven cascade reaction and ameliorates temozolomide-mediated glioblastoma suppression.

Glioblastoma (GBM), the most aggressive WHO grade 4 brain tumor, has a median survival of ~15 months and a five-year survival rate of only 7%. The current surgical and chemotherapeutic approaches remain insufficient for its treatment. A major obstacle in its treatment is the presence of hostile tumor microenvironment (...