Open access
Aug 2026
Characterizing the interaction of a type VII-secreted antimycobacterial toxin with its small helical partner proteins
A structural model of the EatA N-terminal domain in complex with TapA1 and TapA2 is investigated using site-directed mutagenesis and bacterial 2-hybrid assays, and results are consistent with the three proteins forming a stacked bundle of α-helices.
Eunice K. E. Lee, Kieran Bowran, Eleanor R. Boardman et al.
· bioRxiv · 0 citations