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Author

Toshiya Nishimura

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Nov 2026

Adult hematopoietic stem cells activate a normally fetal-restricted program to functionally expand ex vivo.

The ability to robustly expand transplantable hematopoietic stem cells (HSCs) ex vivo enables basic science and clinical therapies otherwise hindered by the scarcity of these self-renewing multipotent cells. Despite recent improvements in long-term ex vivo HSC expansion conditions, the molecular mechanisms required for...

Kyomi J. Igarashi, M. Nicholls, Leonid Olender et al. · 0 citations

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