Author

Tong Wang

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Open access Sep 2026

RUNX1 links ATF4-associated stress adaptation to microenvironmental remodeling in POSTN+ fibroblasts during skin fibrosis

Abstract Background Skin fibrosis encompasses a spectrum of disorders and includes hypertrophic scar (HTS), keloid scar (KS), and systemic sclerosis (SSc), but the pathogenic fibroblast states and shared upstream regulators contributing to these conditions remain incompletely defined. As a common form of skin fibrosis,...

Bin-Yu Song, Yu-Han Zhu, Xiang Wang et al. · Burns & Trauma · 0 citations

Aug 2026

CircRNA hsa_circ_0001946 promotes hypertrophic scar pathogenesis via the miR-514a-3p/COL5A2 axis.

It is established that hsa_circ_0001946 promotes HS development by sequestering miR-514a-3p to derepress COL5A2 expression, suggesting hsa_circ_0001946 as a promising intervention target for mitigating pathological scarring.

Yi Shi, Ya-Juan Song, Tong Wang et al. · Pathology, Research and Prac... · 0 citations