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Author

Tong-Hua Yang

2 papers indexed here

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Clinical trial Oct 2026

Felzartamab plus lenalidomide-dexamethasone versus lenalidomide-dexamethasone for relapsed or refractory multiple myeloma: an open-label, parallel-controlled, randomised, phase 3 trial.

BACKGROUND Complement-dependent cytotoxicity (CDC) of CD38 monoclonal antibodies has been associated with infusion-related reactions and might contribute to reduced clinical efficacy of CDC-reliant CD38 antibodies, particularly in patients with relapsed or refractory multiple myeloma with 1q21+. We aimed to evaluate fe...

Hai-Yan He, J. Shang, Ya-Fei Wang et al. · 0 citations
Sep 2026

Si-Si-Gu-Ben granules alleviate diarrhea-predominant irritable bowel syndrome by modulating gut microbiota and suppressing the TLR4/NF-κB pathway: A combined clinical and animal study.

ETHNOPHARMACOLOGICAL RELEVANCE Si-Si-Gu-Ben (SSGB), a traditional Chinese medicinal formula derived from the theory of "warming the spleen and kidney to arrest diarrhea," is frequently prescribed for diarrhea-predominant irritable bowel syndrome (IBS-D) in clinical practice, yet its pharmacological mechanisms remain in...

Yun-Jiao Xu, Wen-Di Wu, Zhi-Bi Zhang et al. · 0 citations

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