Tomohiro Kohama

Exogenous pressure during in vitro follicle growth suppresses oocyte size expansion without impairing functional competence.

Pressure stimuli, such as those arising from physical forces and hydrostatic pressure in vivo, are known to regulate cellular differentiation and growth. In the ovarian microenvironment, such cues are important regulators of folliculogenesis; however, their roles during in vitro follicle growth remain unclear. This stu...