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Author

Tobias Alexander

2 papers indexed here

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Open access Oct 2026

Single-cell mass cytometry cartography highlights systemic lupus erythematosus and Sjögren’s disease immune differences

Autoimmune diseases such as primary Sjögren’s disease (pSjD) and systemic lupus erythematosus (SLE) share clinical and serological features, including type I interferon signatures, autoantibody formation, and chronic inflammation, but the underlying immunopathology is not the same. To support the development of tar...

F. Szelinski, Ana-Luisa Stefanski, A. Wiedemann et al. · 0 citations
Open access Aug 2026

Single-cell Unperturbed Activation Profiling by mass cytometry captures in vivo immune signaling in SLE

It is demonstrated that single-cell UACT without restimulation of cells can detect immune activation in chronic inflammatory diseases, supporting both biomarker discovery and the identification of novel therapeutic targets.

M. Burns, Lennard Ostendorf, Amro Abbas et al. · 0 citations

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