A biomimetic core-shell nanofibrous dressing for temporally coordinated infection control and mitochondrial protection in diabetic wounds
Chronic infected diabetic wounds are driven by a self-reinforcing pathological cycle of bacterial infection, oxidative stress, and immune dysregulation, wherein mitochondrial dysfunction contributes to impaired reparative macrophage polarization and angiogenesis. To address this, a skin-mimetic core-shell nanofibrous d...