Author

Ting Zhang

2 papers indexed here

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Review Open access Aug 2026

Gut microbiota-derived metabolites and IL-22 signaling in inflammatory bowel disease: context-dependent regulation of mucosal repair and inflammation

It is proposed that the duration and magnitude of IL-22 exposure, its cellular source, the IL-22/IL-22BP balance, epithelial target-cell state, concurrent inflammatory signals, and disease context collectively determine whether IL-22 promotes mucosal repair or contributes to inflammatory amplification.

Pei-Xin Shi, Xi-Yuan He, Ling Zhao et al. · Frontiers in Immunology · 0 citations

Oct 2026

Dehydrocostus lactone attenuates sepsis-associated neuroinflammation by directly targeting JAK2 identified through thermal proteome profiling.

Investigation of the protective effects and target mechanism of DL on CLP-induced septic mice and LPS-stimulated BV2 microglia found it suppressed JAK2 phosphorylation and downstream STAT3 activation, thereby inhibiting neuroinflammatory responses.

Xue-Ling He, Ting Zhang, Xue-Ting Chen et al. · Biochemical Pharmacology · 0 citations