Ting Xue

Engineering Vibrio natriegens for biopesticide production: from pathway optimization to plant protection.

The transcriptional regulator ArcR represses virulence and γ-hemolysin expression in Staphylococcus aureus USA300 LAC.

Staphylococcus aureus is a major opportunistic pathogen responsible for a wide range of infections, and its pathogenicity is tightly controlled by regulatory networks linking metabolism and virulence. ArcR, a member of the Crp/Fnr family that regulates the arginine deiminase (ADI) pathway, has an unclear role in coordi...

Prevention and Treatment of Staphylococcus aureus Biofilms Using Promising Agr-QS-Targeting Anti-Biofilm Agents

The continued exploration of natural biofilm inhibitors anticipates the urgent need for new treatments to combat biofilm-associated infections and multidrug-resistant pathogens like MRSA.

ArlR regulates environmental stress tolerance and biofilm formation in foodborne Staphylococcusaureus

It is demonstrated that deletion of arlR significantly reduces the tolerance of the foodborne strain RMSA49 to acetic acid, desiccation, whereas its responses to temperature and osmotic stress not affected, and that the arlR mutant also exhibits significantly enhanced biofilm formation.

The alternative sigma factor SigH modulates biofilm formation and stress tolerance in a raw milk-derived Staphylococcus aureus.

Findings indicate that SigH contributes to the regulation of persistence-associated phenotypes in a raw milk-derived S. aureus strain and provide new insights into the regulatory mechanisms that may influence survival of this pathogen in dairy-related environments.

The cyclic adenosine monophosphate-ArcRsa signaling axis modulates biofilm formation in dairy-derived Staphylococcus aureus via transcriptional repression of ica operon.

Functional crosstalk between cAMP and ArcRsa through direct regulation at the gene icaA promoter is demonstrated, supporting an essential regulatory role for the cAMP-ArcRsa signaling module in modulating biofilm formation in S. aureus.