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Sep 2026
Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive factor, but rapid loss of bioactivity, short local retention, burst release, and diffusion into surrounding tissues reduce dose efficiency and may necessitate supraphysiological doses associated with local adverse effects. Hydrogels offer tunable platforms...
Ting-Ting Zhou, Xian He, Jia-He Li et al.
· Polymers · 0 citations
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Review
Open access
Sep 2026
Bone-tissue interfaces—including both anatomically-defined structures (osteochondral, tendon-to-bone, ligament-to-bone) with characteristic compositional gradients, and functional biological interactions (bone-immune, bone-vascular, bone-nerve that regulate systemic regenerative processes)—represent critical repair tar...
Xiang-Ran Cui, Pan Xue, Wei Wei et al.
· International Journal of Bio... · 0 citations
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