Author

Tingting Yang

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Open access Sep 2026

Patient-derived organoids enable ex vivo drug-response profiling for precision medicine in bladder cancer

Patient-derived organoids (PDOs) represent a promising precision medicine approach for replicating primary tumor characteristics and facilitating drug testing across various cancers, although clinical evidence in bladder cancer remains limited. This study evaluates the impact of incorporating PDOs into clinical pract...

Si-Jia Li, Feng Qiu, Fang-Yue Zheng et al. · npj Precision Oncology · 0 citations

Jul 2026

A UHPLC-MS/MS method for the simultaneous quantification of BTK inhibitors and their active metabolite in human plasma and cerebrospinal fluid.

This method detects four BTK-related analytes in plasma/CSF with a 3-min run time, evaluation of hemolytic/lipemic matrices, and clinical validation, increasing throughput, reducing costs, and broadening applicability, providing preliminary feasibility data for clinical TDM.

Sijia Li, Jiameng Xie, F. Xia et al. · Bioanalysis · 0 citations