Ting-Ting Li

The eSTKs regulate streptococcal peptidoglycan synthesis with distinct subcellular localizations and coordination with Pbps in S. suis and S. pneumoniae

Compared with traditional drugs targeting penicillin-binding proteins (Pbps), targeting the upstream coordinators of bacterial peptidoglycan (PG) synthesis is a highly promising strategy for overcoming the frequent occurrence of resistance to β-lactam drugs. Eukaryotic-like serine/threonine kinases (eSTKs) are core coo...