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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ting-Ting Huang

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2 papers indexed here

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Review Oct 2026

Toward point-of-care CRISPR-based diagnostics using split crRNA and split activator/target systems.

Split crRNA and split activator/target strategies have enhanced and advanced CRISPR-based diagnostics (CRISPR/Dx) by requiring a conditional assembly of components. The split crRNA involves dividing the guide RNA (crRNA) itself into multiple inactive fragments that only reassemble to become functional crRNA upon bindin...

Cia-Hin Lau, Yu-Mei Huang, Wen-Jie Cai et al. · 0 citations
Open access Sep 2026

4‐2 VHL‐Recruiting PROTAC Inhibits the Growth and Migration of Triple Negative Breast Cancer Cells by Triggering Pyroptosis Through Fas‐Mediated IL‐17 Signaling

SND1 is an oncoprotein found to be overexpressed in breast cancer, especially in triple‐negative breast cancer(TNBC). In our previous study, a novel SND1‐interacting peptide 4‐2 was identified, exhibiting cytotoxicity to TNBC cells by inducing SND1 degradation. This study for the first time demonstrated the degradation...

Qi-Qi Wang, Qiu-Feng Huang, Hui-Ping Ou et al. · 0 citations

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