Ting-Ting Hu

Crystal structures of the N-terminal and C-terminal domains of the SARS-CoV-2 nucleocapsid protein

Crystal structures provided a framework for further investigation of NTD–RNA recognition, the possible role of the CTD positively charged groove in nucleic acid interactions and N-protein assembly and suggest that RNA binding may be accommodated by local side-chain rearrangements within a pre-existing positively charge...