Integrated multi-omics and serological profiling identifies five immunodominant allergens from the high-abundance protein repertoire of Haliotis discus hannai
As the allergens of Haliotis discus hannai (HDH) and their role in human allergy remain limited, we employed an integrated multi-omics strategy combining transcriptome assembly, genome-guided proteogenomics, and quantitative proteomics to systematically profile its allergens, followed by immunobinding assays with aller...