ALKBH5 is identified as a candidate host-cell engineering target for improving recombinant protein production and support further validation under industry-relevant fed-batch conditions.
This review first summarizes the methodologies and advances in CHO omics research, including genomics, transcriptomics, proteomics, metabolomics, metabolomics, and epigenomics, and examines contemporary approaches to integrate and analyze multi-omics data in CHO cells.
Yuan Shen, Lei Shi, Xi Zhang et al.· Bioresources and Bioprocessi...· 0 citations
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