Oct 2026
Matrix-Based Specific T-Cell Activation Reporter for Nearly-Digital Mapping of Antigen-Specific T Cells via Heterotypic Cell Micro-Communities and Digital Microfluidics.
Antigen-specific T cells constitute a low percentage of peripheral blood mononuclear cells (PBMCs) and require antigen presentation by autologous antigen-presenting cells for activation and cytokine secretion. Conventional interferon-γ release assay (IGRA) averages rare activation events beyond cellular resolution, whi...
Hang-Jia Tu, Meng-Xing Mou, Chen-Xuan Hu et al.
· ACS Sensors · 0 citations