Author

Tianyu Tao

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Open access Oct 2026

PRAME Augments K63‐Linked Ubiquitination and Stabilization of METTL3 to Promote Lung Adenocarcinoma Metastasis

It is demonstrated that the significantly upregulated PRAME in metastatic LUAD directly interacts with the m6A methyltransferase METTL3 and promotes its K63‐linked non‐proteolytic ubiquitination, identifying K63‐linked ubiquitination as a previously unrecognized post‐translational modification of METTL3.

Xia Yang, Xue-Mei Xu, Ya-Xuan Zhang et al. · MedComm · 0 citations

Open access Jul 2026

A USP15/KRT17-associated 13-gene prognostic cluster and functional validation in EGFR-mutant lung adenocarcinoma.

A 13-gene prognostic cluster associated with poor survival in EGFR-mutant LUAD is identified and the EGFR-regulated USP15/KRT17 axis is position as a novel framework for patient risk stratification, with potential implications for guiding targeted therapeutic strategies.

Jia-ming Huang, Yi Huang, Qiurong Yuan et al. · Respiratory Research · 0 citations