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Tian-Rui Gu

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Open access Sep 2026

Tailoring lipid nanoparticles for application-specific mRNA delivery.

This study proposes an application-oriented re-engineering strategy that leverages the clinically validated SM-102 platform, enabling rational LNP optimization for diverse mRNA delivery and therapeutic scenarios and recommends SM-102/DSPC and SM-102/DOPE LNPs as preferred formulations for RAW 264.7 macrophages and IGRO...

Xin-Xin Yan, Li-Xin Lin, Yi-Fan Zhang et al. · 0 citations

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