Tian-Qing Wang

Chronic stress drives tumorigenesis and progression via central nervous system-mediated neuroimmune circuits

Chronic exposure to severe social and environmental stressors is a major risk factor for tumor initiation and progression, yet the central nervous system (CNS)-driven mechanisms linking stress to cancer immunity remain poorly defined. Here, we identify activation of the hypothalamic-pituitary-bone marrow (HPB) axis as...