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Author

Tian-Qi Wang

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2 papers indexed here

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Open access Sep 2026

Functional screening of ZIP8 naturally occurring variants identifies pathogenic mutations and trafficking defects.

A workflow to functionally evaluate ZIP8 variants by integrating laser ablation inductively coupled plasma time-of-flight mass spectrometry with scaled-up cell-based transport assays is developed and provides new insights into the structure-function relationships of ZIP8.

Michael Nikolovski, Tian-Qi Wang, Aaron Sue et al. · 0 citations
#protein folding Open access Sep 2026

Symmetry analysis and ancestral sequence reconstruction reveal a symmetrical translocation pathway and activity determinants of ZIP metal transporters.

Membrane transporters frequently exhibit internal structural symmetry, reflecting evolutionary origins through gene duplication and fusion events, and this feature has been widely used to infer transport mechanisms. Yet its application to the Zrt-/Irt-like protein (ZIP) family of divalent metal transporters, which are...

Yao Zhang, Tian-Qi Wang, Hong-Yan Zhao et al. · 0 citations

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