Multifunctional Hybrid Nanomedicines for Neurodegenerative Diseases: A Paradigm Shift from Rational Design to Clinical Translation
Abstract Effective drug delivery to the central nervous system remains a persistent challenge owing to the blood–brain barrier (BBB), heterogeneous pathological microenvironments, and the limited capacity of conventional carriers to achieve precise spatiotemporal control over drug release. Multifunctional hybrid nanome...