Author

Tian-Lei Ying

2 papers indexed here

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Review Open access Aug 2026

Targeting Immune Cell Metabolism for Cancer Immunotherapy

Metabolic reprogramming is a fundamental regulator of immune cell fate and function in the tumor microenvironment (TME), though the relative contributions of individual metabolic pathways vary across immune cell subsets, tumor types, and disease stages. Competition for nutrients, hypoxia, and the accumulation of immuno...

Yi-Qing Jiang, Yan-Ling Wu, Tian-Lei Ying · Cancer Biome and Targeted Th... · 0 citations

Preprint Aug 2026

Is Retrieval All You Need? Assessment and Emergence of Novelty in Protein Structure Generation

RetFold is proposed, a zero-training baseline that constructs backbones by retrieving CATH domains and refining inter-domain connections through geometry-based helix-linker optimization, at two orders of magnitude lower cost on CPU alone.

Tongyu Xu, Yijie Zhang, Mutian He et al. · 0 citations