Tian-Fei Fan

Alveolar macrophage heterogeneity in pulmonary hypertension: pathogenic mechanisms and precision intervention.

Pulmonary hypertension (PH) involves complex interactions between immune dysfunction and pulmonary vascular remodeling. Alveolar macrophages (AMs) are important regulators linking pulmonary immune responses to vascular pathology. However, AMs are not a homogeneous population and undergo dynamic functional reprogramming...