Author

Tian-Chen Li

3 papers indexed here

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Aug 2026

Hierarchical Interfacial Engineering of Gas Diffusion Electrodes for Acidic CO2 Electroreduction in Membrane Electrode Assemblies.

Acidic CO2 electroreduction in membrane electrode assemblies suppresses parasitic carbonate formation and improves carbon utilization. Yet, practical implementations remain hindered by proton accumulation and alkali cation buildup that give rise to failure modes associated with hydrogen evolution, salt precipitation, a...

Anmol Mathur, Yan-Sheng Liu, Zheng-Yuan Li et al. · Journal of the American Chem... · 0 citations

#protein folding Sep 2026

A conformational switch governs the dual role of liquid–liquid phase separation in amyloid fibrillization

Biomolecular condensates provide dynamic environments that store and organize proteins, yet the fundamental principles determining whether condensation promotes or suppresses irreversible protein aggregation remain unclear. Here, we show that the receptor-interacting protein kinase 3 (RIPK3) RHIM domain follows distinc...

Tian-Chen Li, Brayden C. Williams, Qi Han et al. · bioRxiv · 0 citations

Review Open access Sep 2026

Probing biomolecular condensates with a minimally perturbative experimental readout framework

Abstract Biomolecular condensates are membrane-less compartments formed through phase separation that concentrate and organize biomolecules within cells. Far from being static droplets, they are dynamic molecular assemblies whose internal dynamics, structure, mechanics, and composition can evolve over time during cellu...

Jia-Xing Xie, Benedict Tai, Tian-Chen Li et al. · Biochemical Journal · 0 citations