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Ti-Cheng Chang

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Open access Aug 2026

nf-core/pacsomatic: a scalable somatic analytic pipeline using PacBio HiFi data

Abstract Motivation Pacific Biosciences (PacBio) HiFi long-read sequencing enables robust characterization of complex genomic regions, repetitive elements, and structural variants (SVs) that are often inaccessible to short-read technologies. To fully leverage HiFi reads to advance cancer genomics and epigenetics, resea...

Wen-Chao Zhang, Hai-Dong Yi, Bei-Fang Niu et al. · 0 citations
Jul 2026

An epigenetic polarity governing T cell tolerance for commensal microbiota 2250947

The study depicts an epigenetic polarity governing Treg-mediated immune tolerance, highlighting a fundamental asymmetry at the epigenetic level that differentially regulates Treg and conventional T cells.

Wenjun Huang, Yongqiang Feng, Jun Li et al. · 0 citations

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