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Author

Thomas J. Rust

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Open access Oct 2026

Comparative effectiveness of trimethoprim-sulfamethoxazole dosing strategies for Pneumocystis jirovecii pneumonia: a target trial emulation.

OBJECTIVES Trimethoprim-sulfamethoxazole (TMP-SMX) is considered first-line therapy for Pneumocystis pneumonia (PCP); however, dosing recommendations have remained largely unchanged since the 1970s. Current dosing may increase adverse effects without clear beneficial outcomes. This study evaluated the comparative effec...

Revanth S. Yendamuri, Thomas J. Rust, Kyle D. Brizendine et al. · 0 citations

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