Thirumalaikumaran Rathinam

Formulation and Optimization of Sustained-Release Gastroretentive Microspheres of Vonoprazan Using Box– Behnken Design

Background: Vonoprazan is a novel potassium-competitive acid blocker (P-CAB) with potent acid-suppressive activity; however, its therapeutic efficacy may be limited by rapid gastric emptying. The present study aimed to formulate and optimize sustained-release gastroretentive microspheres of vonoprazan using the ionotro...

Drug Repurposing in Polycystic Ovary Syndrome: Bridging Metabolic, Endocrine, and Reproductive Therapeutics

Multi-target Drug Discovery for Cancer Therapy: A Contemporary Review.

MKIs and bispecific antibodies represent transformative modalities in modern oncology, supported by robust clinical evidence and extensive patent activity.