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Taylor G. Gonzalez

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Open access Jul 2026

Anionic lipids regulate PLCβ membrane recruitment

Phospholipase C-β (PLCβ) enzymes are essential effectors of G protein-coupled receptor signaling that hydrolyze phosphatidylinositol 4,5-bisphosphate (PIP2) at the plasma membrane to generate the second messengers inositol trisphosphate and diacylglycerol. PLCβs play essential roles in diverse physiological processes,...

M. D. Crawford, Marie B. Bennett, Yu Qin et al. · 0 citations

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