Breast cancer (BC) is leading cause of cancer-related mortality among women worldwide, with approximately 2.3 million new cases and 670,000 deaths reported in 2022. Despite advances in therapy, challenges such as drug resistance and adverse side effects necessitate the exploration of alternative treatments, particula...
Nazifa Patel, Adil Ali, Tarun Kumar Upadhyay et al.· Journal of King Saud Univers...· 0 citations
The optimized nanoemulsion-based in situ gel demonstrated sustained drug release, enhanced nasal permeation, acceptable safety, and improved antidepressant efficacy and Pharmacodynamic evaluation showed significantly greater reduction in depressive-like behaviours than oral escitalopram solution.
Vahid Vikram Minglani, Meenakshi Patel, Tarun Kumar Upadhyay· DARU Journal of Pharmaceutic...· 1 citation
The study identifies LY2784544 and Pimobendan as potential antiviral agents for Mpro, given their stability, strong binding energy (BE) profiles, and existing clinical data, these compounds warrant additional experimental validation to determine their potential efficacy against SARS-CoV-2.
M. Alam, Lina I. Alnajjar, Tarun Kumar Upadhyay et al.· Journal of King Saud Univers...· 0 citations
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