Tariq Z. Abolibda

Synthesis, Cytotoxic Evaluation, Molecular Docking, and In Silico ADME Studies of Novel Quinazolinone-Based Aldazine Derivatives Using Chitosan Sulfonic Acid as a Recyclable Catalyst

A series of novel quinazolinone-based aldazine and ketazine derivatives (4a–l and 6) was synthesized through the condensation of hydrazine intermediate 2 with substituted aldehydes and isatin using chitosan sulfonic acid (CS–SO3H) as a recyclable heterogeneous catalyst. The reactions were performed under conventional r...