Open access
Oct 2026
Germline DDX41 defines a distinct subgroup in MDS undergoing transplantation with reduced relapse and improved survival.
Germline DDX41 variants are a recognized cause of adult myelodysplastic neoplasms (MDS), characterized by distinct biological features and favorable prognosis. The independent effect of DDX41 status on outcomes after allogeneic transplantation, the role of conditioning intensity, and treatment-related toxicity risk rem...
N. Gagelmann, Christopher R. Reilly, Archana Sasi et al.
· Blood · 0 citations