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Author

Tao Wang

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Open access Aug 2026

Lipid metabolism dysregulation in Parkinson’s disease: A Mendelian randomization and transcriptomic analysis

An integrative analysis identified DGKD, LEP, and GGPS1 as lipid metabolism-associated molecular signatures of PD and highlights GGPS1-mediated prenylation pathways as a potential mechanistic axis linking metabolic dysregulation to neurodegeneration.

F. Çalıkuşu, Su-Xiang Chen, Tao Wang et al. · 0 citations
Jul 2026

Esculetin ameliorates autism-like behaviors in GABAergic neuron-specific Pax2 knockdown mice, accompanied by reduced Wnt/β-catenin signaling.

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with an unclear pathogenesis. Growing evidence implicates excitatory/inhibitory (E/I) imbalance in ASD pathophysiology, prompting an investigation into gamma-aminobutyric acid (GABA)-mediated inhibitory transmission. The transcription factor Paired Box 2 (...

Ningxia Zhang, Liting Xue, Shuqi Chai et al. · 0 citations

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