Review
Oct 2026
Emerging Roles of Mass Spectrometry-Based Proteomics in Drug Discovery.
Ka Yang, Wei-Ping Tang, Tao-Sheng Chen et al.
· Annual Review of Pharmacolog... · 0 citations
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Aug 2026
BRD4 recruitment into HP1 condensates desilences transcription without erasure of repressive chromatin
Christopher J. Brandon, Sarah Robinson-Thiewes, Mangesh H. Kaulage et al.
· Nature Cell Biology · 1 citation
Open access
Jul 2026
Receptor allostery promotes context-specific Sonic Hedgehog signaling during embryonic development
Sonic Hedgehog (SHH) signaling functions in temporal- and context-dependent manners to pattern diverse tissues during embryogenesis. The signal transducer Smoothened (SMO) is induced by sterols, oxysterols, and arachidonic acid (AA) through binding pockets in its extracellular cysteine-rich domain (CRD) and 7-transmemb...
M. Dillard, Christina A. Daly, Rojalin Pradhan et al.
· Nature Communications · 0 citations