The retrosplenial cortex (RSP) supports spatial cognition, memory, and brain-wide information integration, yet its output architecture remains poorly resolved at single-neuron resolution. Using fluorescence micro-optical sectioning tomography (fMOST), we reconstruct sparsely labeled neurons sampled predominantly from t...
Yu-Xiao Li, Tao Jiang, Hui Gong et al.· Cell Reports· 0 citations
Reconstructed brain-wide input and output architecture of three neuronal subtypes, CeASst, CeAPkc-δ, and CeACrh neurons, at single-cell resolution in male mice demonstrate a multilevel, subtype-specific, and lateralized architecture linking molecular identity to brain-wide CeA connectivity.
Lung-Chuang Wang, Wei Song, Xu Chen et al.· Journal of Neuroscience· 0 citations
This study provides a systematic solution for plaque digitization in neuropathological mesoscopic high-resolution images and offers a practical tool to advance AD pathology research.