Author

Tao Cheng

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Open access Sep 2026

KLF4/MLL3 complex axis drives NRBP2 transcription to eliminate acute myeloid leukemia cells.

A molecular mechanism by which KLF4 governs AML progression is revealed, providing a novel therapeutic target and a potential small-molecule inhibitor for AML treatment.

Meng Yang, Ting Lu, Yi-Cheng He et al. · Leukemia · 0 citations

Aug 2026

Engineered lipid nanoparticles for in vivo and durable editing of haematopoietic stem cells within humanized mice.

An LNP is reported that efficiently delivers reporter mRNA to human HSPCs both in ex vivo and in vivo settings when conjugated with the anti-CD34 antibody (CD34/LNPDP).

Jingjing Du, Zijin Luo, Dan Xie et al. · Nature Biomedical Engineerin... · 2 citations