Open access
Sep 2026
Preclinical evaluation of JQ1 in esophageal squamous cell carcinoma: growth and migration suppression with BRD4-associated DNA damage and apoptotic signaling
The findings support further investigation of BET/BRD4-associated pharmacological strategies in ESCC, while target-specific validation and expanded in vivo mechanistic and safety studies remain warranted.
Chun-Lan Pu, Jian-Yu Liu, Heng-Rui Fan et al.
· Frontiers in Pharmacology · 0 citations