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Tanvir Khaliq

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Open access Sep 2026

One-Step Synthesis of Dihydropyrroloquinazolinone Alkaloid Natural Products: S‑(−)- and R‑(+)-Vasicinone and Their Novel Analogues

A single-step synthesis of the biologically active dihydropyrroloquinazolinone alkaloid natural products, S-(−)- and R-(+)-vasicinone (5 and 6) has been developed for the first time. This reaction employs a POCl3-mediated coupling of methyl 2-aminobenzoate with either (S)- or (R)-3-hydroxypyrrolidin-2-one resulting in...

Tanvir Khaliq, Veerpal Kaur · 0 citations

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