Author

Tanmay Tanna

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Open access Aug 2026

An end-to-end computational framework for “Record-seq” transcriptional recording data

To address the primary computational bottleneck of spacer sequence extraction, a wavefront alignment approach is implemented for efficient quasi-local pattern matching, achieving an approximately 30-fold speedup and introducing transcription unit-based feature counting as an alternative to gene-body quantification to b...

Florian Hugi, Tanmay Tanna, Randall J. Platt · Bioinformatics · 0 citations

Open access Jul 2026

A tumor profiling resource for ovarian cancer: insights into chemotherapy-driven heterogeneity and personalized treatment strategy

It is demonstrated that integrated multimodal tumor profiling can inform personalized maintenance treatment decisions and that chemotherapy reshapes tumor cell diversity.

Francis Jacob, R. Wegmann, Joanna Ficek-Pascual et al. · Nature Communications · 0 citations