Ta-Jung Peng

PKM2 is the Metabolic Checkpoint for Stemness Features in Head and Neck Cancer

Owing to their self-renewal, differentiation capabilities, and increased chemoresistance, cancer stem cells (CSCs) are associated with poor prognosis and an elevated chance of relapse and metastasis. CSCs survive under therapy-imposed pressure and aggravate tumor malignancy through metabolic reprogramming, leading to t...