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Open access Aug 2026

Determination of drug sensitivity in patient derived models of breast cancer by multiparametric quantitative phase imaging

Functional precision oncology aims to guide therapy selection by directly measuring drug sensitivity in patient-derived cancer samples. However, most existing functional assays require prolonged cell expansion limiting their feasibility for time-sensitive clinical decision-making. We evaluated whether multiparame...

Edward R. Polanco, Tarek E. Moustafa, Ozlen Balcioglu et al. · 0 citations
Open access Aug 2026

Temporal dynamics improves machine learning-based prediction of cell state from quantitative phase imaging

Cell morphology reflects cell health and can distinguish cell-cycle stage, growth arrest, and distinct pathways of cell death. Live, label-free quantitative phase imaging (QPI) captures these features non-invasively and with high temporal resolution, yet many image-based classifiers rely on single frames and cannot sep...

S. Alizada, Kayla Marks, R. Zitnay et al. · 0 citations

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